Welcome to the ILSI Research Foundation / Risk Science Institute (ILSI RF/RSI) Website.
ILSI RF/RSI works to advance the field of health and environmental risk assessment by:
WHAT'S NEW
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Evaluating the Human Relevance of Modes of Action in Animals
The ILSI Research Foundation presented a successful workshop at the University of North Carolina Friday Center February 12, 2008. Attendance at the workshop exceeded expectations of the organizers; there were a total of 43 participants. Participants came from government agencies (EPA, NIEHS) and industry (Bayer CropSciences, BASF Corporation, Syngenta, GlaxoSmithKline, ILS Inc, Merial Limited). Additionally, in attendance were a number of students from the Curriculum in Toxicology at the University of North Carolina. The workshop featured opening remarks by Dr. George Gray, EPA Assistant Administrator for Research and Development, speaking on “Advancing Risk Assessment at EPA”, and a Plenary Lecture given by Dr. James Swenberg, UNC Chapel Hill titled “Key Events for a Mutagenic MOA: Implications for Risk Assessment”. Click here for a detailed report on the UNC workshop. The next offering of the workshop will be at the 2008 Toxicology and Risk Assessment Conference in Cincinnati, Ohio on April 17, 2008. Click here for more information on the Cincinnati workshop.
Database of Physiological Parameters for Early Life Stages
The human physiological parameters for early life stages database has been completed. Access to the database is free and available from this website. The database is a reference source of appropriate parameter values for physiologically-based pharmacokinetic (PBPK) or biologically-based dose-response (BBDR) models and subsequent use in risk assessment. For further information, click here.
A new Evaluation Version of CARES is available
Evaluation Version 2.2 Build 7.8.9 Build Date 03/14/2006 includes two major enhancements: 1) A Dietary Minute Module (DMM) for assessing within-day (minute-by-minute) risk from exposure to pesticides that have rapidly reversible effects; and 2) Enhancements to the drinking water module. For more information, click here.
UPCOMING MEETINGS
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ILSI Research Foundation Workshop
Evaluating the Human Relevance of Modes of Action in Animals
The ILSI Research Foundation will present a workshop on the application of a framework for evaluating the human relevance of modes of action in animals on April 17, 2008 at the 2008 Toxicology and Risk Assessment Conference in Cincinnati, OH. Click here for more information.